منابع مشابه
The hypothalamus
What has MCPH got to do with the evolution of human intelligence? It has been suggested that small, cumulative changes in MCPHassociated genes have collectively led to the increase in human brain size. There is a clear relationship between measurable intelligence and brain size within humans and between other mammals. Broadly speaking, herbivores have smaller brains than predators and scavenger...
متن کاملAnatomy of the Hypothalamus. Handbook of the Hypothalamus. Volume 1
This multiauthored text, directed to the contemporary practicing physician, is a compendium of genetic information relevant to clinical practice. It is organized into four parts: fundamentals of clinical genetics, multisystem disease, organ system disease, and genetic counseling. It contains a good review of the basics with careful attention to the usual sources of confusion: statistics, geneti...
متن کاملThe motivated hypothalamus.
FINAL PHYSIOLOGICAL REGULATION of eating resides in the hypothalamus. There signals from the periphery (e.g., leptin, insulin, glucose) activate and inhibit circuits that drive ingestive behavior. Thus leptin and insulin act on neurons in the arcuate nucleus. Leptin inhibits neurons that coexpress neuropeptide Y (NPY) and agouti-related peptide (AGRP) and also activates proopiomelanocortin (POM...
متن کاملThe hypothalamus and hypertension.
Most forms of hypertension are associated with a wide variety of functional changes in the hypothalamus. Alterations in the following substances are discussed: catecholamines, acetylcholine, angiotensin II, natriuretic peptides, vasopressin, nitric oxide, serotonin, GABA, ouabain, neuropeptide Y, opioids, bradykinin, thyrotropin-releasing factor, vasoactive intestinal polypeptide, tachykinins, ...
متن کاملMicroRNAs in the hypothalamus.
MicroRNAs (miRNAs) are short (∼22 nucleotides) non-coding ribonucleic acid (RNA) molecules that negatively regulate the expression of protein-coding genes. Posttranscriptional silencing of target genes by miRNA is initiated by binding to the 3'-untranslated regions of target mRNAs, resulting in specific cleavage and subsequent degradation of the mRNA or by translational repression resulting in ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1972
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5805.99